Elearning has become an important and ubiquitous instructional tool across a broad range of programs in institutions of higher education. This is evident today in nursing education where elearning in a blended approach provides both enormous and flexible opportunities for working nurses to further their education and to engage in continuous professional development for life-long learning. We conducted a pilot study to test the feasibility of participant recruitment, data collection, and online survey in an elearning education program in Malaysia. The conceptual framework developed for the study was based on DeLone and McLean (2003) Information Systems Success Model to examine any mediation effect of student satisfaction on elearning quality and learning outcome among nursing undergraduates in a local elearning program. We used the Partial Least Squares approach to analyze the possible effects on the relationships among the variables studied. The exploration process to determine the feasibility of the preliminary online survey helping to contribute to the main study to be conducted in an elearning nursing context. The findings revealed that there were significant relationships between the dimensions of system quality and service quality with student satisfaction and learning outcome. The results showed that there was a mediating effect of student satisfaction on the relationship between elearning quality and learning outcome. The study emphasizes the importance of an initial understanding of the learning environmental needs of learners to provide a credible and meaningful learning experience for working nurses in elearning nursing programs.