The most recent incarnation of development goals, the Sustainable Development Goals (SDG), call for a more intentional integration of higher education in development. Research can provide an avenue by which this done, developing relevant solutions to social problems. But who benefits from research, and whose knowledge counts in this process? Formal engagement with Indigenous knowledge, honoring the voices, artifacts, histories, traditions, and "knowledges" of those Indigenous communities that buttress the university can potentially contribute to both the social and environmental justice at the heart of sustainable development. Our research was focused on how African academics at two public universities and community members in The Gambia and Zambia constructed the role of Indigenous knowledge within their community-based research activities. We highlight the specific epistemic strategies academic researchers used to engage Indigenous communities and knowledge, the dilemmas faced in the field, and the connections made through research relationships to sustainable development.