The study aimed to examine the effects of secondary school students' gender variable and the variables that could be moderators on their attitudes towards physical education and sports classes. The study adopted the meta-analysis method, which is one of the methods of synthesizing research results, constituted the research model. Within the scope of the study, researches on secondary school students' attitudes towards physical education and sports classes were examined, and the findings obtained constituted the main data source of this study. As a result of the meta-analysis, it was revealed that there was no publication bias. According to the fixed effects model, the average effect size value was d = 0.083 in favor of male students, and 0.081 in the random effects model. As a result of the moderator analysis, it was determined that the researcher (s) was not a moderator for the calculated average effect size of the variables such as gender, research region, research type, class level, research year and sample number. In short, the gender variable had almost no effect on secondary school students' attitudes towards physical education and sports lessons.