Given the high number of immigrant youth in the United States that are from Latinx backgrounds and given that these youth are at risk for experiencing traumatic events during their migration, it is critical for school mental health providers to understand how to best serve this population. To do so, they must first understand how the unique experience of Latinx immigrant youth, especially experiences related to trauma, might affect their mental health. This article will review the relevant literature, with these specific areas of focus: (1) the prevalence of migration-related traumatic experiences among Latinx immigrant youth; (2) the prevalence of traumatic experiences during various stages of the migration experience; (3) the effects of migration-related traumatic experiences on youth's mental health; and (4) the risk and protective factors for experiencing traumatic events and for developing mental health symptoms among Latinx immigrant youth. Implications for practice, including development of cultural competence among mental health providers, use of an ecological framework, and use of trauma-informed services are discussed.