Current estimates are that more than one-third of the annual neonatal deaths worldwide occur in humanitarian and fragile settings (United Nations Population Fund 2015). In this article, we focus on the recent multistakeholder effort to produce the "Roadmap to Accelerate Progress for Every Newborn in Fragile and Humanitarian Settings 2020-2025." This effort, led by Save the Children, the UN Children's Fund, the UN High Commissioner for Refugees, and the World Health Organization, calls for a representation of newborn health issues and action across all phases of emergency response. It specifically emphasizes the need to "engage stakeholders from across humanitarian and development sectors to ensure that mothers and newborns survive and thrive even in the most difficult circumstances" (Save the Children et al. 2020, 5). This commentary also emphasizes basic needs that are vital to the survival and adequate development of newborns, such as avoiding separation from the mother, support for early and exclusive breastfeeding, infection prevention, basic resuscitation, and kangaroo mother care. At the same time, it is critical to establish interventions that create an environment of nurturing care to promote early childhood development.