The study aimed to investigate participants' perceptions of online distance learning during COVID-19 Pandemic for empowering them to achieve ISTE standards within EFL classroom. 60 undergraduate students participated in this study through responding to a designed online survey based on ISTE standards. Data analysis indicated that the participants had a positive attitude of online distance learning which empowered them to develop high scores of creativity and innovation, communication and collaboration, research and information fluency, critical thinking, problem-solving, decision-making and digital citizenship. The results also showed that majority of respondents (86.66%) acquired language proficiency successfully through online distance learning which indicated a flexible and suitable learning environment. However, the findings indicated few drawbacks of online distance learning due to technical problems and the lack of physical interactions. The results suggested that instructors should be aware of the effectiveness of digital technologies as instructional method for empowering their students to achieve ISTE standards within online EFL classroom.