The aim of the research is to investigate the relationship between the preschool teachers attitudes towards science education and their cognitive flexibility levels. In this context, personal information of 207 pre-school teachers was collected with the Personal Information Form prepared by the researcher. Attitude Scale of Preschool Teachers Towards Science Education (Cronbach alpha coefficient: 82) and Flexibility Scale (Cronbach alpha coefficient : 81) used in the research. The Kolmogorov-Smirnov and Shapiro-Wilktest tests were used to determine the distribution of the data and Mann-Whitney U and Kruskall Wallis H tests were used in the research. It was seen that there was a positive and significant relationship between pre-school teachers' attitudes towards science education and cognitive flexibility levels.