This article looks at what origin stories teach about the world and what kind of material presence they have in Southwestern Amazonia. We examine the ways the Apurinã relate to certain nonhuman entities through their origin story, and our theoretical approach is language materiality, as we are interested in material means of mediating traditional stories. Analogous to the ways that speakers of many other languages who distinguish the entities that they talk to or about, the Apurinã make use of linguistic resources to establish the ways they interact with different entities. Besides these resources, the material means of mediating stories is a crucial tool to narrate the worlds of humans and nonhumans. Storytelling requires material mediation, and a specific context of plant substances. It also involves community meeting as a space of trust in order to become a communicative practice and effectively introduce the history of the people. Our sources are ethnography, language documentation, and autoethnography.