This paper examines the ability of a public higher education in Ghana to adapt to changes in teaching and learning in the midst of COVID-19 pandemic. Measures taken to ensure uninterrupted migration to online teaching and learning included a regular monthly supply of data bundle from an internet service provider to faculty members, select support staff and students in addition to regular training in the effective use of the SAKAI Learning Management System. Challenges encountered include inadequate internet access, occasional network interruptions during online classes and oversubscription of Zoom time slots at the departmental level. Despite these challenges, this public higher education institution was able to complete the 2019/2020 academic year fairly well.