Poverty alleviation by education is the soul of reshaping the development of impoverished areas. In the implementation of poverty alleviation, the collaborative model of impoverished areas driven by developed regions is essential for China's poverty alleviation work. In 2016, Changxing County, Huzhou City, Zhejiang Province, and Zhijin County, Bijie City, Guizhou Province, established a counterpart support relationship. According to Zhijin County's education assistance needs, Changxing County has gathered its strength to implement management input, demonstration guidance, and training guidance for its weak schools. With vocational education as the starting point, Zhijin County has been "remodeled" and "implanted" education assistance and has achieved a win-win situation. This article takes the education counterpart support activities of Changxing County and Zhijin County as an example to explore the path and methods of regional education assistance in China under the vision of collaboration.