Although the extent of the damage caused by the COVID-19 pandemic in Africa is unknown, its effect on the socioeconomic and geopolitical spheres is becoming palpable. Its impact on communication and social formations is evident as it has shifted such to a more spatial and virtual sphere. The closure of schools does not only interfere with the traditional patterns of socialization but intercepts the academic sequence and plunges ill-prepared educational systems reminiscent of African universities into a cosmos of teaching and learning uncertainties. How prepared are African universities to cope with the threats to its educational systems and adapt or influence the transition? Despite having a teeming youth birth into technology, are they cognitively and technically adept to teach or be taught within the accredited online e-learning platforms? While the safety measures announced by African governments in relation to the closing of educational institutions and the banning of gatherings have a negative impact on the continuation of teaching, learning and research activities of higher education institutions, it could also be seen as an opportunity.