This study investigated the relationship between quality of life level and social appearance anxiety levels of physically disabled boccia athletes. The population of 2018-2019 Boccia Championships for the Physically Disabled Turkey was invited to participate (N = 97 athletes), and sampling was determined by simple random sampling (n = 83); data from 80 athletes were used. The quantitative study was performed by applying the linkage method to the screening model. Questionnaire technique was used as the data collection method. The descriptive form, quality of life scale, and social appearance anxiety scale were applied to the participants. Correlation and regression analysis were used for statistical analysis. When the direction and level of the relationship between quality of life and social appearance anxiety were examined, a high level and positive relationship between quality of life and social appearance anxiety was found. There is a significant relationship between quality of life and social appearance anxiety. Regression coefficient values of quality of life level contribute to social appearance anxiety level. As a result, a high and negative relationship was found between quality of life and social appearance anxiety. This study found that the quality of life level of the physically disabled individuals engaged in boccia sport contributed to social appearance anxiety level. In other words, it has been determined that the determinants of quality of life are an important or priority variable in social appearance anxiety of physically disabled boccia athletes.