Child inactivity, overweightness, and obesity are recognized problems in the United States. Despite characterization as an "epidemic," children continue to fall short in meeting physical activity recommendations necessary to maintain proper health. Relevant literature indicates that after-school programs (ASPs) are viable options for promoting physical activity (PA) in youth. Little research has investigated the PA of children identified as overweight or obese within ASPs. The purpose of this study was to describe PA engagement during an ASP focused on promoting healthy lifestyles in overweight and obese children with regard to PA, nutrition, and emotional well-being. Results indicated differences in step counts, minutes of activity, and minutes engaged in moderate to vigorous physical activity between participant groups and between different lessons within the ASP curriculum. Findings indicate that curriculum, lesson objectives, and the nature of games and activities influence the amount of PA achieved by children in ASPs.