Electronic portfolios (e-portfolios) have been widely used to help learners collect evidence of their learning, reflect on their evaluation, and promote self-directed learning. Through the introduction of an e-portfolio platform in a cluster of lessons in a module in a polytechnic in Singapore, this paper aimed to evaluate the effectiveness of the e-portfolio through the learners' perceptions. A cross-sectional design using an online survey was employed with 226 students taking part in this study. There was high internal consistency among the survey items. Exploratory factor analysis suggested a 5-factor structure: (1) perceived usefulness (PU); (2) organisation (ORG); (3) collaboration (COL); (4) evaluation (EVA); and (5) perceived value of learning (PVL). In addition, confirmatory factor analysis verified that the proposed 5-factor solution was a good model fit. The final research instrument comprised 19 items. A further multiple regression analysis showed that all the independent variables, except for evaluation, were positive and significant predictors of learners' PVL. Specifically, the ORG variable was the most influential predictor of PVL. In comparison, the PU variable was a relatively weaker predictor of PVL. The practical implications and further direction for research are discussed in the paper.