This paper aims to summarise peer-reviewed literature into the mental health of transgender young people within a secondary schooling environment. A scoping review was conducted using literature across four databases. The search was limited to English language peer-reviewed articles that reported upon the association between school factors and the mental health outcomes of transgender young people in secondary schools. The review resulted in seven relevant studies, which reported numerous school factors related to mental health outcomes for transgender young people. The factors that related to mental health of transgender young people in schools include peer victimisation and bullying, perceived safety and a sense of school belonging or connectedness. Clinical and practical implications are provided for policy makers, educational institutions and school mental healthcare professionals. It is recommended that future research is needed to investigate the mental health services provided within the schooling environment.