The purpose of this article is meant to provide evidence and examples from an exemplary middle school science teacher's classroom with regard for using innovative approaches in STEM education. The author of the article suggests moving from a curriculum-centered paradigm to a student-centered paradigm. Strategies for integration in STEM education are discussed, and include choice-based centers, project-based learning, and small group instruction. The role of standards and curriculum are addressed with an emphasis on whole child, developmental practices, and meaningful/relevant activities in science education.