In this study job satisfaction among employees of education offices in Assosa zone was examined. Sixty-five regional education bureau and 50 woreda education office employees were selected with proportional stratified random sampling. One sample t-test, independent samples t-test, one-way ANOVA, and linear regression were used for data analysis. The findings revealed that employees were significantly dissatisfied. Regarding organizational location, there were no significant differences in satisfaction between employees of regional education bureau and woreda education offices except working condition, supervision, and organizational policies and practice. This finding also indicated that the dissatisfaction level of employees of woreda education offices were more severe in relation to working condition and supervision, whereas in terms of organizational policies and practice employees of education bureau were more dissatisfied. Additionally, the study indicated that working experience and educational level have no effect on overall satisfaction of the participants. However, there was significant satisfaction difference in advancement with regard to working experience. The findings indicated that the Zone administrators need to consider to take the variables affecting the satisfaction of the employees in job placement, advancement, and promoting too.