Our essay examines the challenges and opportunities for the New York City Universal Pre-K program in Catholic Schools. We review the impact of the program before and during the COVID-19 pandemic. These Pre-K programs have brought much needed revenue for Catholic Schools and provide a pipeline for prospective Catholic K-12 school students. Specifically, we discuss the school choice context in New York City with attention to the Catholic school sector and how Universal Pre-K fits into it. We then make recommendations on how the Archdiocese of New York and the Diocese of Brooklyn can utilize their resources, maintain enrollment, and support the broader community during this challenging time. We base our recommendations on our various roles as researchers of school choice, professors of Catholic K-12 school faculty, and personal involvement of one of the authors on Catholic school boards. Although our essay focuses on New York City, the implications apply to the Catholic school sector in many metropolitan areas.