The main aim of this study is to comparatively examine the "Studying and Learning Strategies" used by the students of Science and Anatolian High Schools, which are the general secondary instruction level in the Turkish Educational System, at Adana province example in Turkey. The study is a descriptive study, a relational survey model. The population of the study is 9th and 12th grade students who are studying in Anatolian and Science High Schools in the city center of Adana. This study group of this research is consisted of 393 students in 9th and 12th grades who were studying at Adana Science High School and Seyhan IMKB Anatolian High School in the spring term of the 2019-2020 academic year. As a data collection tool, the "Study and Learning Strategies Scale for High School Students" developed by Kutlu, Yapici and Korkmaz (2015), consisting of 46 items and five sub-dimensions, was used. As a result of the study, when the "Study and Learning Strategies" of the students are examined according to school types, it has been determined that there is a significant difference in the sub-dimensions of "Repetition" and "Enjoying Learning". It has been observed that there is a significant difference between male and female students in "Repetition" and "Self-Confidence" sub-dimensions according to the gender of the students. There is no significant difference between the levels of 9th and 12th grade students studying at Science and Anatolian High Schools according to their grade levels.