This study examined the influence of cultural resources (ethnic identity, Afrocentric worldview, and religiosity) on suicidal thoughts and behaviors among Black college students and the role of personal resources (ego resiliency and optimism) as mediators of this link. Data collected from 257 participants were analyzed. A bivariate correlational analysis showed that ethnic identity was significantly associated with lower levels of suicidality. In addition, ego resiliency mediated the relationships between Afrocentric worldview, ethnic identity, and religiosity and suicidality.