Occupational health physiotherapy is an evolving clinical speciality which requires advanced clinical practice skills and organisational knowledge. There is a dearth of studies in the literature addressing frameworks for occupational health physiotherapy practice. In response, the Association of Chartered Physiotherapists in Occupational Health and Ergonomics (ACPOHE) developed an Occupational Health Framework for Physiotherapists, however, the development of this framework was limited to the expert opinions of physiotherapists. A doctoral study was, therefore, undertaken to explore the role of occupational health physiotherapy from the perspectives of stakeholders outside the physiotherapy profession in order to develop a multiple-perspective conceptual framework. The aim of this paper is to present a discussion on the core concepts emerging from the conceptual framework. Furthermore, an overview of the legal and policy framework that underpins occupational health physiotherapy practice, the process to develop the framework and the use of the framework in practice is presented.