Aim of this study was to examine motor skills and quality of life values of Turkish children according to age and gender factor, and to examine the relationship between motor skills and quality of life values. The sample of the study comprised of 434 students in 8--10 age group (X¯= 9.17±0.80 years; BMI = 17.46±3.05 kg/m2; Weight = 32.45±8.30 kg; Height = 135.19±10.18 cm) who attended the primary schools in the city center of the province of Usak, Turkey. Health-Related Quality of Life Questionnaire-Family Form (KINDL-FF) and Bruininks-Oseretsky Test of Motor Proficiency-2nd Version (BOT-2)-Short Form were employed in order to evaluate the students' quality of life and their motor skills. Mann-Whitney U test, Kruskal-Wallis test and Spearman Correlation test were applied to analyze variables. There was a significant difference between all of the motor skill values except manual dexterity and family sub-dimension of quality of life by gender (p< 0.05). A significant difference was found between all motor skills' parameters and school sub-dimension by age factor (p < 0.05). While a positive correlation was found between the total quality of life and the fine motor precision, fine motor integration, balance, running speed & agility and total motor skill values (p< 0.05), no correlation was found between the other parameters (p> 0.05). In line with the data obtained from the present study, children of the 8-10 age group should be directed to perform various physical activities that will support motor skills and health. Increasing their health behaviors that will positively affect the motor skills may improve their quality of life as well.