Digital and print readings differ in their affordances. Past research supports a print advantage, but few studies have used within-subjects approaches or compared handheld devices and multiple reading genres. We compared college students' reading of several excerpts on paper, a laptop, and an e-reader. Students read on all platforms, completed comprehension tasks, and answered questions on their perceptions and preferences. Results indicated that students' learning experience with print was superior, with the laptop a close second. In contrast, students' learning from and perceptions of the e-reader were lower. There was no interaction with reading genre. This research suggests that students' preference for print remains strong. When digital materials are used, e-readers appear to be a less viable option for academics relative to laptops.