Given the wide range of academic content and 21st-century college and career readiness (CCR) skills that need to be targeted in secondary classrooms, teachers must be prepared to plan and implement a variety of strategies to ensure the progress and participation of each student, including those with extensive support needs. The purpose of this article is to describe the Unit Co-Planning Guide (UCPG) to guide teachers to: (1) plan academic content with integrated development opportunities for CCR skills, such as critical thinking, communication, collaboration, and creativity; (2) consider the needs of all students with universal design for learning (UDL); (3) identify specific student goals and preferences; and (4) design individualized supports, including embedded instruction, curricular adaptations, peer supports, and personnel supports. The intended use of the UCPG is to support collaboration between teachers in the design of academic and nonacademic content delivered to inclusive secondary classes with particular focus on the supports necessary to facilitate involvement and progress for students with extensive support needs.