This study aims to investigate the effect of mixed reality applications on students' motivation to learn science. The study further aims to identify students' attitudes toward augmented reality applications and also intends to explore the students' views on mixed reality applications. A total of 42 primary school students participated in the study for a duration of 8 weeks. The results of the study indicate that mixed reality applications are effective in students' motivation for collaborative work in science teaching. In this context, it can be stated that mixed reality applications can make a significant contribution to the students' potential of collaboration with their peers. In the research, it was concluded that students were willing to use the augmented reality applications in science teaching and their anxiety levels decreased. The results obtained reveal that students are pleased to use augmented reality applications in science teaching. Qualitative data obtained from student views also support the quantitative results. The majority of the students stated that mixed reality applications should be employed in all courses and expressed that they are excited about the use of these applications and feel motivated for science teaching.