In this study, it was aimed to investigate the effect of virtual reality usage in science teaching on 100 students attending 6th grade in Orhaneli district of Bursa province in 2017-2018 academic year. The study was designed as an experimental model of quantitative research methods. The Cell Knowledge Test developed by the researcher in the experimental and control groups generated by random assignment was applied separately before and after the cell subject was processed. In the experimental group, before and after the use of virtual reality applications which were adapted by the researcher, the attitude levels towards the course and the differences between these levels were revealed with the help of an Attitude Scale towards Science and Technology Course. As a result of the research, it was concluded that the use of virtual reality technology in the cell subject teaching has a significant effect on students' achievement and attitudes towards the course.