(1.1) Background: Research assent is a term used with those deemed vulnerable, for whom modifications and additional considerations are required when requesting their voluntary agreement to participate in research. (1.2) Methods: The authors' research experiences and inclusive research principles were integrated with a review of literature on research assent with individuals with significant learning disabilities. (1.3) Findings: Vulnerability can be reconceived through the value and voice of participation in research. We provide practical suggestions for those who oversee social science research, as well as offer guidance to researchers considering inclusive research but for whom practical considerations are required. (1.4) Conclusion: To enhance participant diversity and a generative contribution to knowledge, consideration about research assent is needed. The absence from research can perpetuate exclusion from society.