This essay showcases cognitive psychology and neuroscience research as the "one thing" that guides my work. This research shows how to learn on one's own, paves the way for student success, and fosters inclusive teaching. These principles have implications for concrete classroom and online instructional practices that are easy for both faculty and students to implement. Because students have to attend to and process their learning experiences, faculty must motivate them to do so. Psychology offers us some useful, albeit limited, tools, and more research on ways we can help students set goals can reduce the limits.