My objective in this article is to consider the implications of Bernard Stiegler's theory of the neganthropocene for the politics of knowledge and education. Stiegler sets out his theory of the neganthropocene in his recent books, Automatic Society and The Neganthropocene, in order to respond to what he writes about in terms of the entropic conditions of the hyper-industrial society of the anthropocene. In this respect Stiegler extends his earlier work on hominisation, technics, technology, and hyper-industrialisation to take in the concept of the anthropocene and related environmental, ecological concerns. In this article I set out Stiegler's theory of the neganthropocene, before thinking through the politics of knowledge and education that could make this utopian transformation from an ecologically unsustainable to a sustainable society possible. What would the politics of knowledge of the neganthropocene look like and how would they work in the context of the (global) education system?