ERIC Number: EJ1233553
Record Type: Journal
Publication Date: 2019-Aug
Pages: 7
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-2473-3806
EISSN: N/A
Infantile Spasms: The Role of Prenatal Stress and Altered GABA Signaling
Schuck, Maria; Swanson, Christina I.
HAPS Educator, v23 n2 p420-425 Aug 2019
Infantile spasms (IS) is a rare epileptic disorder occurring in children under the age of one that can often lead to severe developmental delays throughout life. Though over 200 etiologies have been associated with this disorder, many cases remain unexplained. Research into the etiology of IS has implicated causes such as exposure to prenatal stress or changes in GABAergic signaling. Here, we describe recent findings that draw a direct connection between prenatal stress, altered GABA signaling, and the development of IS. We also discuss how these findings can be used in the classroom to enrich discussions of nervous system physiology, development, and disease.
Descriptors: Epilepsy, Infants, Stress Variables, Prenatal Influences, Genetic Disorders, Neurological Organization, Neurological Impairments, Brain, Pregnancy, Physiology
Human Anatomy and Physiology Society. PO Box 2945, LeGrange, GA 30421. e-mail: editor@hapsconnect.org; Web site: https://www.hapsweb.org/page/hapsed_home
Publication Type: Journal Articles; Reports - Descriptive
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A