This paper examines the role of technical and vocational education and training (TVET) in Palestine through an economic and social development lens, and identifies the lessons learned. The paper discusses the effect of TVET on employment within the notion of decent work, poverty reduction, and empowerment of youth, within a context of marginalization, extracting lessons learned and policy implications to ensure equity and inclusion in TVET and labor markets. The paper also illustrates the effect of TVET on marginalized communities. The case and experience of Palestine can be of value to other countries from various perspectives. The analysis of the marginalized groups engaged in TVET could present a framework of measurement of the effect of TVET on these different groups within a marginalized context that could be of benefit to fragile and conflict-affected states elsewhere.