Studying in overseas institutions presents international students with exciting opportunities; however, with these opportunities come challenges. Drawing on literature since the year 2000, this article addresses challenges confronting international students within some top sending countries and receiving countries. The challenges are categorized into pre-departure, post-departure, and post-study. The findings revealed pre-departure challenges, such as obtaining accurate information, understanding the admission procedure, and preparing documents for visa acquisition. Post-departure, international students face language barriers, financial issues, and cultural adjustment when they are in the host countries. Uncertain future and paperwork are the major challenges post-study. The findings of this article have useful implications for government personnel, as well as administrators of educational institutions that seek to attract international students.