Popular science sphere of communication is acquiring new features of virtuality, globality, mosaic structure and social orientation, which are essential in fulfilling its functions in modern society. Based on the examination of 92 podcasts, the study deals with podcasting research identifying typical characteristics of the podcast and factors contributing to the spread of podcasting in the popular scientific hypermedia communication. The survey showed that increasing popularity of the podcast in the popular scientific sphere is explained by several factors. First, informing the user becomes more accessible, quicker and easier. Secondly, the listener takes part in interpersonal communication not with a virtual author, but with a real person, gets the opportunity to make his own conclusions based on sounding speech, which is more expressive, emotional, and has a strong impact on the addressee. Thirdly, most podcasts are interviews and discussions, which facilitates the perception and processing of new information making it more structured by means of questions, paraphrasing, exemplification, clarifications, etc. Analysis of the Nature publication podcast helped single out structural features that allow a podcast to function in a hypermedia environment as an independent multimodal node. The conclusions about the emergence of new virtual environment for intercultural interaction and cooperation were made.