Maternal perinatal depression is not an uncommon experience, yet few mothers are identified and treated--a concerning fact, given the potential for negative impact on both maternal and infant well-being. In the present study, I review recent research in the field of maternal perinatal depression and highlight associated developmental outcomes among offspring in physiological, cognitive, behavioural, and socio-emotional domains. Developmental outcomes--and more specifically, the pathways by which these outcomes develop--are explored among offspring in infancy, childhood, and adolescence. Specific attention is given to research exploring (at both macro- and micro levels) the interactional processes that occur between mothers with depression and their offspring. Ultimately, the review identifies a need to continue to develop and apply novel research methodologies to further understand the interactional processes that occur between mothers and their offspring in the context of maternal depression, and specifically how these interactions develop across the span of offspring development.