This study explores measures of curiosity and autonomy as two motivation and personality predictors of personal growth initiative (PGI), an indicator of cross-cultural adjustment. The sample comprised 221 international graduate students. Structural equation modeling was utilized to identify the relations among self-perceived language skills, curiosity, autonomy, and PGI. The results indicate that perceived language skills and autonomy promote curiosity, which in turn facilitates PGI. Implications are suggested to facilitate the adaptation of international students.