To support employment of individuals with severe disabilities, instructional approaches for improving independent performance are urgently needed. The purpose of this research was to assess the effects of TEACCH structured teaching on the independent work skills of individuals with severe disabilities in a job setting. A multiple probe across participants design was used for this study. Results demonstrated that structured teaching was effective in enhancing engagement and reducing disruptive behavior in three individuals with severe disabilities in the absence of adult prompting. In addition, their performance was generalized in a different job setting.