This study evaluated an on-campus leadership and culture program that helps newly arrived international students with their cross-cultural adjustment. The international student participants completed an acculturation survey at both the beginning and the end of the program. We found that factors causing these international students to have stressful adjustment experiences included the new environment, perceptions of discrimination, worry about access to opportunities due to cultural differences, and feelings of discomfort with others. Many program participants experienced positive changes in their adjustment to the new environment. The results suggest, however, that not all international students would benefit from participating in the program. The findings provide important insights for on-campus programs that aim to facilitate international students' cross-cultural adjustment.