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ERIC Number: EJ1184452
Record Type: Journal
Publication Date: 2018-Aug
Pages: 13
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-0162-3257
EISSN: N/A
Maternal Exposures Associated with Autism Spectrum Disorder in Jamaican Children
Christian, MacKinsey A.; Samms-Vaughan, Maureen; Lee, MinJae; Bressler, Jan; Hessabi, Manouchehr; Grove, Megan L.; Shakespeare-Pellington, Sydonnie; Coore Desai, Charlene; Reece, Jody-Ann; Loveland, Katherine A.; Boerwinkle, Eric; Rahbar, Mohammad H.
Journal of Autism and Developmental Disorders, v48 n8 p2766-2778 Aug 2018
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with poorly understood etiology. Many maternal exposures during pregnancy and breastfeeding potentially interfere with neurodevelopment. Using data from two age- and sex-matched case-control studies in Jamaica (n = 298 pairs), results of conditional logistic regression analyses suggest that maternal exposures to fever or infection (matched odds ratio (MOR) = 3.12, 95% CI 1.74-5.60), physical trauma (MOR 2.02, 95% CI 1.01-4.05), and oil-based paints (MOR 1.99, 95% CI 1.14-3.46) may be associated with ASD. Additionally, maternal exposure to oil-based paints may modify the relationship between maternal exposure to pesticides and ASD, which deepens our understanding of the association between pesticides and ASD.
Springer. Available from: Springer Nature. 233 Spring Street, New York, NY 10013. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-348-4505; e-mail: customerservice@springernature.com; Web site: https://bibliotheek.ehb.be:2123/
Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (NIH); National Institute of Environmental Health Sciences (NIEHS) (NIH); National Center for Research Resources (NIH/DHHS); National Center for Advancing Translational Sciences (NCATS) (DHHS/NIH)
Authoring Institution: N/A
Identifiers - Location: Jamaica
Grant or Contract Numbers: R21HD057808; R01ES022165; UL1RR024148; UL1TR000371