This study examined whether combining classroom curriculum with direct experience with people with disabilities (PWDs) can influence change in undergraduate students' attitudes toward PWDs. Undergraduate students (N = 68) enrolled in a psychology course completed the Interaction with Disabled Persons Scale at the beginning and end of the semester. During the semester, students learned about various disabilities and participated in a 10-hr service-learning project that required direct, supervised interaction with PWDs at a local, nonprofit organization that provides employment services to adults with disabilities. Students reported more positive attitudes toward PWDs at the end of the semester. Having an increased comfort level in interacting with PWDs can give students pursuing careers that involve working with PWDs an advantage.