Prader-Willi Syndrome (PWS) is one of the low-incidence physical disabilities that the literature has not addressed in relation to the Individuals with Disabilities Education Act and its case law applications. To help fill the gap, this relatively brief article provides (a) an introduction of PWS from legal sources; (b) an overview of the IDEA, including its primary components and alternate decisional avenues; (c) a synthesis of the case law to date, which amounts to a limited variety of administrative and judicial decisions; and (d) a brief set of conclusions from an impartial legal perspective.