This study sought to examine the activities that go on in physics classrooms in Senior High Schools in Ghana. Specifically, the study sought to investigate the pattern of interaction and instructional methods used for teaching physics and level of coverage of physics syllabus. The survey design was employed for the study in which questionnaire was used for data collection. Participants for the study were physics teachers and final year physics students. Findings from the study suggest that classroom interaction seemed to be mostly teacher-centered and tended not to support inquiry-based teaching and learning which is noted for promoting conceptual change and enhance performance. It is recommended among other things that physics teachers should be exposed to efficient pedagogies of teaching and presenting information to learners. The traditional way of teaching where teacher decides on what goes on in the classroom has a limited space in the 21st century science classrooms, particularly physics.