Our objective was to design an introductory business course to shape the mind-sets and skill sets of the next generation of socially conscious practitioners--to help students develop a sense of self-efficacy built on the confidence that they can make a positive impact on the world using entrepreneurial thinking and action. Essentially, the focus was to develop an introductory business course that would encourage and enable students to understand that business can be a force for good (sustainability and social impact) and to practice collaborative innovation (human-centered design thinking). The overarching design principle was "business not as usual," which embraced four themes: (a) sustainability and social entrepreneurship, (b) collaborative innovation, (c) entrepreneurial thinking and action, and (d) self-authorship. We provide an overview of the course modules and their respective learning outcomes along with details of course content and activities to ensure transferability. A concluding discussion shares the impact on students and the challenges of success. We highlight how course design can be a catalyst to enable students to be the change they want to see in the world.