The purpose of this study is to compare the predictive power of prospective teachers' basic needs on self-actualization. This is a correlational research which is one of the descriptive research methods. The study was conducted on 1033 prospective teachers studying in Bulent Ecevit University Eregli Faculty of Education in the spring term of the academic year of 2013-2014. Data were collected with "self-actualization scale" which is subscale of "Healthy Life Style Behaviour Scale" and "University Students' Basic Needs Scale". Pearson product-moment correlation coefficient technique and stepwise-regression analysis were used to analyze the data. As a result of the study, it has been identified that the most effective factor on prospective teachers' self-actualization is the fun need which is one of the sub-dimension of basic needs.