A number of initiatives are aimed at reducing mental illness stigma, yet stigma remains a problem in the general population. A focus on stigma reduction with students is particularly relevant, as students often hold negative attitudes toward mental illness, have regular contact with persons experiencing mental health difficulties, and because stigma influences students' own help-seeking attitudes and behaviors. The psychology classroom presents an ideal opportunity to address stigma, since many courses include mental health-related topics and are taken by large numbers of students from diverse fields. This paper undertook a review of the published literature to determine the extent that knowledge and/or contact-based strategies to address stigma were implemented in the psychology classroom; successful interventions are described and contextualized within the larger stigma reduction literature. Recommendations for instructors who are interested in integrating an anti-stigma approach in their classroom include (1) consider a social contact-based approach, (2) look locally for resources, (3) be familiar with optimal conditions for contact, and (4) evaluate your outcomes.