This study investigated the relevance of multi media skills in teaching and learning of scientific concepts in secondary schools. Self constructed questionnaire was administered to 120 students randomly selected in four secondary schools in Ojo Local Government Area of Lagos state. Data generated were analyzed using chi-square statistical instrument. The findings of the study revealed that the acquisition of relevant skills in multi media will improve teaching and learning of scientific concepts in secondary schools. Based on the findings, recommendations were proffered to inculcate knowledge of multi media skills in improving teaching of science.