Epistemology is defined as theory of knowledge and the ways of achieving it. Epistemology is research questions of the possibility of knowledge and the riddle of knowledge. Epistemology and methodology despite being interconnected are inseparable and are not reducible from each other. In addition, their relationship is direct, meaning that ontology logically precedes epistemology and epistemology proceeds methodology, logically. In other words, it has very close relations with epistemology; there are three types of methodology: proof, interpretive and critical. In this paper, we seek to examine the perspective of Feyerabend's epistemology and its implications in research of methodology. We will first review and analyze the paradigms of research methodology and then, the description of Feyerabend's epistemology, and finally, assess the implications of methodological approach to research in education from Feyerabend's point of view.