This study investigated whether use of alcohol, cigarettes, and marijuana may be predicted from preferential consumption of particular music genres. Undergraduates (257 women and 78 men) completed a questionnaire assessing these variables. Partial correlation analyses, controlling for sensation-seeking tendencies and behaviors, revealed that listening to conventional music (pop, country, and religious genres) was negatively correlated with cigarette smoking (p?=?0.001) and marijuana use (p?<?0.001). Additionally, listening to energetic music (rap or hip-hop and soul or funk genres) was positively correlated with marijuana use (p?=?0.004). The only significant predictor of alcohol use was country music, with which it was positively correlated (p?=?0.04). This research suggests an especially harmful influence of energetic music on marijuana use.