In 2012-2013, leaders and staff of the San Jose Unified School District (SJUSD) focused on accomplishing the district's new mission: to aggressively pursue solutions to close the opportunity gap and ensure that all students leave SJUSD with twenty-first-century skills, prepared to participate in a global society. The district's participation in the College Readiness Indicator Systems (CRIS) initiative presented an opportunity to place the CRIS work within the context of the district's 2012-2017 strategic plan, Opportunity21. The district positioned the CRIS work as a way to establish, validate, and model a process for broad implementation of the district's Key Performance Measures (KPMs)--a set of connected data metrics that signal how well the district is accomplishing its goals. This positioning of CRIS has ensured a coherent K-12 effort by three CRIS schools--Lowell Elementary, Hoover Middle, and Lincoln High, which together create a college readiness pipeline throughout one feeder cluster of schools--and created a model for districtwide rollout of college and career readiness indicators. Three CRIS teams working on indicators at the school and district (setting and systems) levels successfully implemented what the authors refer to as "data intervention cycles," which use data to identify struggling students, match the students with supports, and then evaluate the effectiveness of the supports. The district has used these cycles to begin building a culture of evidence-based practices districtwide.