Including students with special needs in the general education classroom is being widely promoted in the public schools. This practice places a heavy burden on the general educator who is often inadequately trained to meet the needs of such a diverse classroom. Co-teaching has been one of the support strategies used to address the challenges and capitalize on the opportunities for learners with special needs in the general education classroom. This article provides twenty suggestions for high school administrators to consider when implementing co-teaching in order to support the teachers who engage in this promising practice.