Hotel Louisville is owned and operated by Wayside Christian Mission and is staffed by screened and vetted Wayside resident clients. This unique situation, along with the University of Louisville (UofL) partnership, positions both as national exemplars for authentic community involvement with higher education. The purpose of this article is to describe the Hotel Louisville/UofL partnership, discuss the positive impact of UofL's collaboration with Hotel Louisville, and to highlight some of the dramatic successes.